[ANN] MetidaNCA.jl: Noncompartmental PK Analysis (NCA)

MetidaNCA is the package for noncompartmental pharmacokinetic analysis. It’s assumed that the package can be used for batch data analysis. The main calculation methods are implemented:

  • Linear-trapesoidal;
  • Log-trapezoidal;
  • Linear-up, log-down.

Most pharmacokinetic parameters can be obtained.

Documentation available.

Validation in progress. Draft validation report available: validation_report.pdf.

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v0.1.3 released. Better test coverage, better output. Improved validation coverage.

v0.1.4 released. Plotting. Now you cat plot PK profile directly from subject dataset.

Version 0.1.6 released. Improve validation coverage and documentation: more plots and examples. Fix some bugs. Basic routines: setkelrange!, setdosetime!, setkelauto!, applylimitrule! now can be easily applied to set of subjects. You can modify elimination range settings, dosing time and tau, change concentrations if BLLOQ. Added modify! for possibility of calculation custom parameters. Set can be exported as table.

Some plots examples:

plot1

plot3

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Version 0.2.1 released.

Validation report extended.

Urine PK implemented.

Other minor code changes.

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