If you are looking for affine transforms, CoordinateTransformations.jl or ImageTransformations.jl may be what you need.
https://juliaimages.org/ImageTransformations.jl/stable/
Also see this recording of the image processing workshop from JuliaCon 2023:
@tim.holy , the presenter, also happens to be a microscopist. You might find some of his lab’s packages useful as well.
@RainerHeintzmann and his lab group also have some microscopy utilities available: