I am not sure whether I am interpreting your question correctly, but I think the answer is yes. Here is an example with Makie:
With a sysimage that took just a couple of clicks to prepare in vscode:
julia> @time @eval using CairoMakie
0.008680 seconds (14.54 k allocations: 927.412 KiB)
julia> @time plot([1,2,3])
2.082096 seconds (1.94 M allocations: 130.274 MiB, 2.15% gc time, 37.41% compilation time)
Without a custom sysimage:
julia> @time @eval using CairoMakie
13.082514 seconds (17.49 M allocations: 1.247 GiB, 4.57% gc time, 3.01% compilation time: <1% of which was recompilation)
# don't even bother actually making the first plot, it takes more than 30 seconds