If you know the size of your data, you can explicitly specify the input range:
julia> DataFrame(load("test.xlsx", "Sheet1!A2:B5"))
3×2 DataFrames.DataFrame
│ Row │ test1 │ test2 │
├─────┼───────┼───────┤
│ 1 │ 1.0 │ 4.0 │
│ 2 │ 2.0 │ 5.0 │
│ 3 │ 3.0 │ 6.0 │
edit: looks like it might be better to use ExcelReaders.jl, which skips blank starting lines by default, or allows you to skip some number of lines:
readxlsheet("test.xlsx", "Sheet1", skipstartrows=1) |> DataFrame