# In silico clinical trials in Julia without using Pumas

**URL:** <https://discourse.julialang.org/t/in-silico-clinical-trials-in-julia-without-using-pumas/138049>\
**Category:** General Usage\
**Created:** [July 10, 2026, 4:47am UTC](https://discourse.julialang.org/t/in-silico-clinical-trials-in-julia-without-using-pumas/138049 "2026-07-10T04:47:47Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![arinbasu](https://sea2.discourse-cdn.com/julialang/user_avatar/discourse.julialang.org/arinbasu/32/581_2.png) [@arinbasu](https://discourse.julialang.org/u/arinbasu)\
**Post date:** [July 10, 2026, 4:47am UTC](https://discourse.julialang.org/t/in-silico-clinical-trials-in-julia-without-using-pumas/138049/1 "2026-07-10T04:47:47Z")

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Hi All,  
I am interested to know if anyone has any suggestions about packages other than Pumas for in silico clinical trials for Julia. I have been using DifferentialEquations and SciML for simple simulations but is it possible to combine DifferentialEquations, ModelingToolkit, JuliaNLM & Turing for non-linear mixed effects models. Unfortuantely even though I want to install Pumas if it were as Pluto Notebook in JuliaHub, it does not seem like it is possible to do so, hence the request.  
Would greatly appreciate any pointers to tutorials or solutions.  
Kind Regards,  
Arindam

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**Author:** ![PharmCat](https://sea2.discourse-cdn.com/julialang/user_avatar/discourse.julialang.org/pharmcat/32/6953_2.png) [@PharmCat](https://discourse.julialang.org/u/PharmCat)\
**Post date:** [July 10, 2026, 11:16am UTC](https://discourse.julialang.org/t/in-silico-clinical-trials-in-julia-without-using-pumas/138049/2 "2026-07-10T11:16:28Z")

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Hi! At this moment I’m also using DifferentialEquations and Turing in my work. There are no alternatives for Pumas in the Julia ecosystem right now. I hope one will appear, or maybe I’ll start doing something in this direction someday ))

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**Author:** ![vjd](https://sea2.discourse-cdn.com/julialang/user_avatar/discourse.julialang.org/vjd/32/2644_2.png) [@vjd](https://discourse.julialang.org/u/vjd)\
**Post date:** [July 10, 2026, 11:44am UTC](https://discourse.julialang.org/t/in-silico-clinical-trials-in-julia-without-using-pumas/138049/3 "2026-07-10T11:44:03Z")

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@arinbasu you can request an academic license (if you are in academia) or reach out to PumasAI to use Pumas. They are friendly people out there 😀

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**Author:** ![andreasnoack](https://sea2.discourse-cdn.com/julialang/user_avatar/discourse.julialang.org/andreasnoack/32/27_2.png) [@andreasnoack](https://discourse.julialang.org/u/andreasnoack)\
**Post date:** [July 29, 2026, 7:29am UTC](https://discourse.julialang.org/t/in-silico-clinical-trials-in-julia-without-using-pumas/138049/4 "2026-07-29T07:29:11Z")

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> [@arinbasu](#):
>
> Unfortuantely even though I want to install Pumas if it were as Pluto Notebook in JuliaHub, it does not seem like it is possible to do so, hence the request.

@arinbasu Would you be able to elaborate on this part? Do you have access to Pumas but are unable to use it with Pluto, or do you not have access to Pumas at all?
